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Completed
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes (External Link)
A blood sample will be obtained to start making the CTLs before the patient begins chemotherapy. The patients EBV-specific T cells will be grown while the patient is being treated …
Baylor Role:
Lead Sponsor
Completed
Evaluation of Calcium, Vitamin D, Magnesium, and Zinc Absorption in Children (External Link)
We plan to stratify subjects for randomization to either vitamin D supplements or placebo by serum 25-hydroxyvitamin D (25 OHD) into three groups: 0-20 ng/mL, 20-32 ng/mL, and >32 ng/mL. …
Baylor Role:
Lead Sponsor
Completed
MethaCholine Bronchoprovocation Study (MeCIS) (External Link)
The study consists of two phases. The first phase is a cross-sectional, case-control study measuring the sensitivity and specificity of methacholine challenge testing for differentiating asthmatic participants from non-asthmatic controls. …
Baylor Role:
Collaborator
Completed
Impact of Vitamin D Status on Bones in Breastfed Infants (External Link)
In recent years, severe vitamin D deficiency has resurfaced as a major public health concern. Nutritional rickets is widespread, and a recent report on this disease in Texas showed Hispanic …
Baylor Role:
Lead Sponsor
Terminated
Testosterone for Penile Rehabilitation After Radical Prostatectomy (External Link)
There was only one patient who began treatment with the study drug. After blind was broken, it was noted that he received placebo Testim and Viagra.
Completed
Research Study for Children With Salt Wasting Congenital Adrenal Hyperplasia (External Link)
The adrenal gland is a small organ of the body. It produces very important chemicals called hormones. One of these hormones, cortisol (the stress hormone) helps the body fight diseases. …
Baylor Role:
Lead Sponsor
Withdrawn
Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department (External Link)
This study is a health outcomes intervention trial that utilizes a randomized clinical trial (non-placebo controlled) with two separate arms. The study will be conducted in the ED of Texas …
Baylor Role:
Lead Sponsor
Terminated
Steroid Treatment for Sickle Cell Pain Crisis (External Link)
In the United States, 9% of African Americans have sickle cell trait and 1 in 600 has sickle cell disease. Vaso- occlusive crises in sickle cell disease remain a frequent …
Baylor Role:
Lead Sponsor
Completed
Novel Treatment for Diastolic Heart Failure in Women (External Link)
Subjects with diastolic heart failure defined based on clinical symptoms, echocardiography diastology parameters and brain natriuretic peptide level will be randomized in a 1:1 fashion to either placebo or spironolactone …
Baylor Role:
Lead Sponsor
Completed
Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease (External Link)
The study will be prospective. Patients who meet entry criteria will be randomized to receive corticosteroids versus placebo. Randomization will take into account biventricular versus univentricular repairs/palliations and whether the …
Baylor Role:
Lead Sponsor