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Terminated
Effect of Dapagliflozin on Inflammation and Endothelial Function (External Link)
The insulin-resistant state of type 2 diabetes mellitus (T2DM) is largely mediated by inflammatory pathways affecting skeletal muscle which is the primary site of whole body insulin resistance. Nuclear factor …
Baylor Role: Lead Sponsor
Terminated
Treatment of Adult Patients With Hemoglobin SC Disease (SCYTHE) (External Link)
Patients will be recruited from the patient population followed at the Texas Children's Cancer and Hematology Centers (TCC/HC)/Baylor College of Medicine (BCM) and the University of Texas Houston Hematology Center. …
Baylor Role: Lead Sponsor
Terminated
Transcorporal Versus Standard Artificial Urinary Sphincter Placement (External Link)
Procedure/ Methods: Patients will be identified in the urology clinic upon their standard of care visit for AUS placement. The procedures that determine whether a patient is a surgical candidate …
Baylor Role: Collaborator
Terminated
Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft (External Link)
Urethral strictures affect 1% of men and are rare in women. Most urethral strictures in the United States develop in the bulbar section of the urethra which is the section …
Baylor Role: Collaborator
Terminated
The Utility of Time Segmental Withdrawal During Screening Colonoscopy for Increasing Adenoma Detection Rate. (External Link)
Screening colonoscopy is an essential diagnostic tool in the early detection of precancerous colonic lesions, preventing the progression of these lesions to cancer. Population-based and case control studies found a …
Baylor Role: Lead Sponsor
Terminated
Human Optokinetic Contrast Device (HOCD) to Measure Visual Function and Identify Patients With and Without Glaucoma (External Link)
The protocol is divided into two studies that will have two separate consent forms (Study 1 and Study 2). Study 1 involves the optimization of the device parameters. Study 1 …
Terminated
Sertraline in Treatment of Low-Risk Myelodysplastic Syndrome (External Link)
This pilot study investigates clinical benefit of four 28-day cycles of sertraline in low-risk MDS patients. Participants will receive 100mg of oral sertraline daily. The study will also evaluate potential …
Baylor Role: Collaborator
Terminated
Fetal Cystoscopy for Lower Urinary Tract Obstruction (External Link)
Patients with severe LUTO will come for clinical evaluation as part of the standard clinical care at the Fetal Center at Texas Children's Hospital. Once the diagnosis of fetal severe …
Baylor Role: Lead Sponsor
Terminated
Treatment of Hemoglobin SC Disease With Hydroxyurea (External Link)
To be eligible to participate in this study, patients must have HbSC disease, have experienced a sickle cell disease related complication, or have a score of 80 or lower on …
Baylor Role: Lead Sponsor
Terminated
Comparing Nasal Suction Devices in Children With Bronchiolitis: A Pilot Study (External Link)
Bronchiolitis is a viral illness and a common cause for admission to the hospital. Most patients with bronchiolitis are managed at home. The indications of hospitalization are poor feeding (due …
Baylor Role: Lead Sponsor