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Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity (External Link)
This study aims to evaluate the effects of oral glycine supplementation on plasma glycine concentration, intracellular glutathione (GSH) concentration, plasma acylglycine concentration, urine acylglycine concentration, and insulin resistance in subjects …
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Genetic Disorders of Obesity Program Database (External Link)
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children …
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Lead Sponsor
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Causal Mechanisms in Adolescent Arterial Stiffness (External Link)
Aortic stiffness measured in adolescence or adulthood determines current hypertension, predicts future incidence of hypertension, and future atherosclerotic cardiovascular disease (ASCVD) events. International hypertension guidelines list severe aortic stiffness as …
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Lead Sponsor
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Preventing Persistent Post-Surgical Pain and Dysfunction (External Link)
Persistent post-surgical pain (PPSP) is a common and debilitating problem following surgery.1 Orthopedic surgeries, such as Total Knee Arthoplasty (TKA), are consistently associated with high postoperative pain, putting patients at …
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Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program? (External Link)
AIM 1: We will categorize children ages 7-12 yrs. of age with FGIDs (n=250) as to whether they have/do not have one or more of the following abnormal physiologic changes: …
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Pediatric Gastroparesis Registry (External Link)
In the Pediatric Gastroparesis Registry (PGpR), we will collect detailed epidemiological, clinical, psychological, and patient outcome data with the goal of classifying patients with gastroparesis and gastroparesis-like syndromes into pathophysiologically …
Baylor Role:
Collaborator
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Reading Remediation and Outcomes in Detention (External Link)
Learning disabilities (LD) are among the most common types of disabilities in juvenile offenders that have been linked to delinquency. Nationwide, children and youth with special education needs are overrepresented …
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Lead Sponsor
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Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism (External Link)
After age of 40, testosterone (T) production in men gradually decreases at a rate of 1.6% per year for total and to 2-3% per year for bioavailable T. This reduction …
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Lead Sponsor
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Safety and Efficacy of Endoscopic Assisted Push Gastrostomy Using Gastrostomy Technique (External Link)
This is a retrospective chart review. We will review charts of patients who underwent gastrostomy with gastropexy and primary percutaneous gastrostomy tube placement with pull through technique and compare immediate …
Baylor Role:
Collaborator
Recruiting
New Pediatric Patching Method to Improve Compliance (External Link)
Patients will present to the pediatric ophthalmology clinic at Texas Children's Hospital. If during the course of their standard care visit it is determined by their pediatric ophthalmologist or optometrist …
Baylor Role:
Lead Sponsor