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Active, Not Recruiting
DiaBetter Together for Young Adults With Type 1 Diabetes (External Link)
DiaBetter Together is a strengths based peer support intervention delivered to young adults (age 17-25) by trained Peer Mentors (age 20-35) during the transition between pediatric and adult diabetes care. …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Houston "Breathe Easy" Healthy Homes-Based Model for Multifamily Rental Communities (External Link)
This is a pragmatic randomized clinical trial that examines the effectiveness of a clinically informed phone-based environmental intervention for improving asthma control in individuals living in selected Houston Housing Authority …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Adolescent Sexually Transmitted Infection Screening in the Emergency Department (External Link)
Adolescents are disproportionately affected by sexually transmitted infections (STIs). The STI epidemic among youth is a national public health priority as noted in the Healthy People 2020 objectives, which specifically …
Baylor Role: Collaborator
Active, Not Recruiting
BCG Vaccine for Health Care Workers as Defense Against COVID 19 (External Link)
Study design: A placebo-controlled adaptive multi-center randomized controlled trial. Study population: High risk HCW with direct patient contacts, defined as physician assistants, respiratory therapists, nurses, physicians or other HCWs working …
Baylor Role: Collaborator
Active, Not Recruiting
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome (External Link)
Investigators will measure pre-determined biomarkers with known or suspected association with ARDS severity or outcome. Simultaneously, investigators will measure gene expression of peripheral blood. Both plasma biomarkers and gene expression …
Baylor Role: Collaborator
Active, Not Recruiting
Development of Adaptive Deep Brain Stimulation for OCD (External Link)
ENROLLMENT: A subject is considered enrolled upon signing informed consent, deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patient¿s family and …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults (External Link)
The study will recruit up to 290 healthy adult males and non-pregnant females into a two-part clinical trial of a vaccine to protect against schistosomiasis caused by infection with S. …
Baylor Role: Lead Sponsor
Active, Not Recruiting
MTG201 Plus Nivolumab in Patients With Relapsed Pleural Mesothelioma (External Link)
This is a study of the efficacy and safety of MTG201 given by intratumoral injection to patients with malignant pleural mesothelioma who have failed front line chemotherapy. Patients will also …
Baylor Role: Collaborator
Active, Not Recruiting
Eltrombopag vs Standard Front Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children (External Link)
This is a prospective, open label, randomized, two-arm, multi-center Phase 3 trial. Patients with newly diagnosed ITP are randomized 2:1 to receive the experimental treatment, eltrombopag, or investigator's choice of …
Baylor Role: Lead Sponsor
Active, Not Recruiting
C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) (External Link)
To prepare the T cells (GD2-C7R T cells), research staff will take some blood from the patient. We will grow the GD2.C7R T cells by infecting the T cells with …
Baylor Role: Lead Sponsor