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Search Clinical Trials
Recruiting
Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL) (External Link)
A healthy donor has given blood to make LMP/BARF1/EBNA-1 MABEL CTLs in the lab. We made the cells by first growing a special type of cells called activated T cells …
Baylor Role:
Lead Sponsor
Recruiting
Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae (External Link)
Open-label, dose-escalation clinical study in healthy, hookworm-naïve adults: - Study site: George Washington Medical Faculty Associates, Washington, DC - Number of participants: up to 30 in 3 cohorts of 10 …
Baylor Role:
Lead Sponsor
Recruiting
Standardized Prenatal Clinical Care for LUTO (External Link)
Patients with LUTO will come for clinical evaluation as part of the standard clinical care at the our Fetal Center. The standardized prenatal management of plan for fetuses with LUTO …
Baylor Role:
Lead Sponsor
Recruiting
New Pediatric Patching Method to Improve Compliance (External Link)
Patients will present to the pediatric ophthalmology clinic at Texas Children's Hospital. If during the course of their standard care visit it is determined by their pediatric ophthalmologist or optometrist …
Baylor Role:
Lead Sponsor
Recruiting
Sickle Cell Clinical Research and Intervention Program (External Link)
The St. Jude Pediatric SCD Program has developed a comprehensive plan of care that spans the ages of 0 to 25, and provides the structure for screening and monitoring disease …
Baylor Role:
Collaborator
Recruiting
Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN) (External Link)
Patients will give the investigators blood to make CD19 CD28 (with and without CD137) chimeric receptor-T cells in the laboratory. These cells will be grown and frozen. To make the …
Baylor Role:
Lead Sponsor
Recruiting
High Resolution Microendoscopy for the Detection of Esophageal Squamous Cell Neoplasia (External Link)
Our central hypothesis is that HRME can improve the efficiency and clinical impact of endoscopic screening and surveillance of esophageal squamous cell neoplasia by providing in-vivo optical biopsies comparable to …
Baylor Role:
Collaborator
Recruiting
Natural History Study of GATA2 Deficiency and Related Disorders (External Link)
Mutations in GATA2, a critical hematopoietic transcription factor, underlie a complex congenital disorder characterized by immunodeficiency, bone marrow failure, and lymphatic/vascular dysfunction. Patients with GATA2 deficiency may suffer from a …
Baylor Role:
Collaborator
Recruiting
Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment (External Link)
Study overview. This cross-sectional prospective observational study of patients with CoA previously treated using one of three treatment modalities assesses if treatment type is associated with differences in vascular function. …
Baylor Role:
Collaborator
Recruiting
Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE (External Link)
Subjects (or their syngeneic donor) will give blood for investigators to make EBV-specific (GRALE) T cells in the lab. These cells will be grown and frozen for the subject. The …
Baylor Role:
Lead Sponsor