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Completed
Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE') (External Link)
Poor retention in HIV primary care results in lower rates of HIV viral suppression, higher rates of HIV transmission, and exacerbates racial and ethnic disparities in health outcomes, including survival. …
Baylor Role:
Lead Sponsor
Recruiting
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV (External Link)
Although the prevalence of smoking has declined over the past 50 years, large disparities in tobacco use remain across several subgroups, particularly disadvantaged and health compromised populations. In fact, the …
Baylor Role:
Collaborator
Recruiting
Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting (External Link)
Treatment-resistant depression (TRD) is a major worldwide burden. Major depression has a lifetime prevalence of ~15% across developed countries. Up to a third of patients fail to respond adequately to …
Baylor Role:
Lead Sponsor
Recruiting
Preventing Persistent Post-Surgical Pain and Dysfunction (External Link)
Persistent post-surgical pain (PPSP) is a common and debilitating problem following surgery.1 Orthopedic surgeries, such as Total Knee Arthoplasty (TKA), are consistently associated with high postoperative pain, putting patients at …
Baylor Role:
Collaborator
Completed
Peer-led Group Intervention for Coping With Disaster (External Link)
Approximately 20% of individuals have significant behavioral health concerns. Exposure to a disaster like Hurricane Harvey and its aftermath often exacerbates pre-existing issues and/or brings new issues, with post-traumatic stress …
Baylor Role:
Lead Sponsor
Withdrawn
Zonisamide Outpatient Study (External Link)
This is a randomized, double-blind, placebo-controlled study to examine the ability of 5-weeks treatment with zonisamide to reduce symptoms of PTSD and AUD. The study population will consist of 60 …
Baylor Role:
Collaborator
Completed
Maternal Mental Health in the Hospital Setting (External Link)
Study participants will complete a survey about their general needs and access to resources and a survey to screen for postpartum depression to determine if the participant will be enrolled. …
Completed
Study to Treat Major Depressive Disorder With a New Medication (External Link)
Depressive disorders are among the most disabling medical conditions worldwide and currently available treatments fall short of addressing this large public health burden. Dysfunction within the brain reward system is …
Baylor Role:
Collaborator
Completed
Telehealth Depression Treatments for Older Adults (External Link)
The long-term objective of the proposed study is to improve access to depression treatments for low-income, racially diverse homebound seniors, a population experiencing significant disparities in mental health care due …
Baylor Role:
Collaborator
Terminated
Adjunctive Transcranial Direct Current Stimulation (External Link)
Chronic or persistent pain is pain that continues when it should not be present; it is ongoing or recurrent pain, lasting beyond the usual course of acute illness or injury, …
Baylor Role:
Lead Sponsor