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Causal Mechanisms in Adolescent Arterial Stiffness (External Link)
Aortic stiffness measured in adolescence or adulthood determines current hypertension, predicts future incidence of hypertension, and future atherosclerotic cardiovascular disease (ASCVD) events. International hypertension guidelines list severe aortic stiffness as …
Baylor Role:
Lead Sponsor
Completed
Obesity-Related Glycine Deficiency: Investigating a Long-standing Metabolic Paradox Using Bedside and Bench Approaches (External Link)
Metabolic tracers: 1,2-[13C2]-Glycine, 1,2-[13C2]-Glycine, 2,3,3,-[2H3]-Serine and [2H5]-Phenylalanine will be infused for quantification of various pathways associated with glycine metabolism.
Baylor Role:
Collaborator
Completed
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers (External Link)
Screen time is a major risk factor for childhood obesity and inadequate physical activity, both of which are determinants of type 2 diabetes (T2D), cardiovascular disease, and multiple cancers. Latinos …
Baylor Role:
Collaborator
Completed
Online Videos and New Feeding Content to Enhance a Current EFNEP Program (External Link)
During Phase I of the project (first two years), the leadership team composed of both research and extension investigators will work with the media production team to edit the SEEDS …
Baylor Role:
Lead Sponsor
Completed
Long-term Lifestyle Change and Testosterone Replacement (External Link)
Background: There are studies on long-term testosterone replacement in older adults with hypogonadism showing benefits on body composition, sexual function and mood but not on testosterone replacement therapy in combination …
Baylor Role:
Lead Sponsor
Completed
Automated Fetal Weight Estimation: A Multicenter Validation Using Fractional Limb Volume (External Link)
Ultrasound has been used for over 20 years to estimate fetal weight prior to birth. Sometimes this estimation is not always similar to what the baby actually weighs. In addition …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants (External Link)
Primary Objective: To evaluate the effects of a high versus standard protein enteral diet utilizing targeted fortification on linear growth in infants < 1000 g birth weight (BW). Hypothesis 1: …
Baylor Role:
Lead Sponsor
Completed
Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot) (External Link)
After the age of 40, testosterone (T) production in men gradually decreases at a rate of 1.6% per year for total and to 2-3% per year for bioavailable T. Because …
Baylor Role:
Lead Sponsor
Completed
Smart and Secure Children Program for Preschool Obesity (External Link)
Thirty (30) subjects will be enrolled across three (3) TCP clinics where the study will take place. Two types of participants will be recruited for this study: parent participants who …
Baylor Role:
Lead Sponsor
Completed
Growth and Microbiome Development in Very Low Birth Weight Infants Fed Primarily Mother's Own Milk vs. Donor Human Milk (External Link)
Background: Human milk feeding provides numerous benefits to preterm infants due to improvements in gastrointestinal maturation, host defense, infection rates, and improved long-term outcomes in neurodevelopment as well as cardiovascular …
Baylor Role:
Lead Sponsor