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Completed
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial (External Link)
Youth between the ages of 13 and 24 accounted for 22% of all new HIV infections in 2015. Less than half (44%) of youth living with HIV (YLWH) in the …
Baylor Role:
Collaborator
Completed
Non Invasive Oral Cancer Screening Among HIV Infected Individuals (External Link)
If you agree to take part in this study, you will be asked to come to the clinic for 2 study visits. First Study Visit: - You will be asked …
Baylor Role:
Collaborator
Completed
Glutathione and Function in HIV Patients (External Link)
Detailed data are not as yet available
Baylor Role:
Lead Sponsor
Completed
Study to Evaluate Safety and Toxicity of Polyphenon E (EGCG) in HIV-1-Infected Individuals (External Link)
HIV-1 infection ultimately results in impaired specific immune function by virtue of the initial binding of the HIV-1 virion envelope glycoprotein 120 (gp120) to the CD4 receptor in complex with …
Baylor Role:
Lead Sponsor
Completed
Role of HIV on Glutathione Synthesis and Oxidative Stress (External Link)
HIV infection is associated the development of increased oxidative stress and deficiency of glutathione (GSH), the dominant endogenous antioxidant protein, but the underlying mechanisms contributing to GSH deficiency are hitherto …
Baylor Role:
Lead Sponsor
Completed
Test of an Intervention to Improve HIV Care (External Link)
At Thomas Street Health Center (TSHC), one of the largest outpatient HIV clinics in the country, we developed a structured, theory-based, Patient Mentor Program to improve retention in HIV primary …
Baylor Role:
Lead Sponsor
Completed
Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children (External Link)
BACKGROUND: HIV-infected children are often given HAART to reduce HIV-associated disease. The long-term effects and toxicities associated with this chronic therapy in children are unknown, but severe cardiotoxicity has been …
Baylor Role:
Collaborator
Completed
Sleep, HIV Disease Progression, and Function in HIV Infected Children and Adolescents (External Link)
BACKGROUND: In the growing number of HIV infected youth and young adults, it is important to study the effects of HAART treatment on sleep patterns and related neurocognitive and psychosocial …
Baylor Role:
Lead Sponsor
Completed
Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia (External Link)
BACKGROUND: HIV lipodystrophy syndrome is associated with both metabolic (e.g., dyslipidemia and insulin resistance) and anthropomorphic (e.g., lipoatrophy and central obesity) abnormalities. These defects are likely to predispose HIV patients …
Baylor Role:
Lead Sponsor
Completed
Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy Syndrome (External Link)
The HIV lipodystrophy syndrome (HLS) is characterized by peripheral fat wasting and central obesity, and hyperlipidemia (mainly hypertriglyceridemia), which results in insulin resistance. HLS patients are at high risk for …
Baylor Role:
Lead Sponsor