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Completed
Get Connected Efficacy Trial (External Link)
The number of HIV infections among men who have sex with men aged 15-24 (YMSM) has grown significantly in the past decade. For YMSM to successfully engage in HIV prevention …
Baylor Role:
Collaborator
Completed
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial (External Link)
Youth between the ages of 13 and 24 accounted for 22% of all new HIV infections in 2015. Less than half (44%) of youth living with HIV (YLWH) in the …
Baylor Role:
Collaborator
Completed
Non Invasive Oral Cancer Screening Among HIV Infected Individuals (External Link)
If you agree to take part in this study, you will be asked to come to the clinic for 2 study visits. First Study Visit: - You will be asked …
Baylor Role:
Collaborator
Completed
Glutathione and Function in HIV Patients (External Link)
Detailed data are not as yet available
Baylor Role:
Lead Sponsor
Recruiting
Natural History Study of GATA2 Deficiency and Related Disorders (External Link)
Mutations in GATA2, a critical hematopoietic transcription factor, underlie a complex congenital disorder characterized by immunodeficiency, bone marrow failure, and lymphatic/vascular dysfunction. Patients with GATA2 deficiency may suffer from a …
Baylor Role:
Collaborator
Completed
Study to Evaluate Safety and Toxicity of Polyphenon E (EGCG) in HIV-1-Infected Individuals (External Link)
HIV-1 infection ultimately results in impaired specific immune function by virtue of the initial binding of the HIV-1 virion envelope glycoprotein 120 (gp120) to the CD4 receptor in complex with …
Baylor Role:
Lead Sponsor
Completed
Role of HIV on Glutathione Synthesis and Oxidative Stress (External Link)
HIV infection is associated the development of increased oxidative stress and deficiency of glutathione (GSH), the dominant endogenous antioxidant protein, but the underlying mechanisms contributing to GSH deficiency are hitherto …
Baylor Role:
Lead Sponsor
Completed
Test of an Intervention to Improve HIV Care (External Link)
At Thomas Street Health Center (TSHC), one of the largest outpatient HIV clinics in the country, we developed a structured, theory-based, Patient Mentor Program to improve retention in HIV primary …
Baylor Role:
Lead Sponsor
Terminated
Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders (External Link)
Donor Stem Cell Processing for Mismatched Donors: Harvested peripheral blood stem cells will be enriched for CD34 cells using the CliniMACS CD34 Reagent system, according to Center for Cell and …
Baylor Role:
Lead Sponsor
Completed
Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children (External Link)
BACKGROUND: HIV-infected children are often given HAART to reduce HIV-associated disease. The long-term effects and toxicities associated with this chronic therapy in children are unknown, but severe cardiotoxicity has been …
Baylor Role:
Collaborator