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CYP19A1 Gene and Pharmacogenetics of Response to Testosterone Therapy
Estrogen has been gaining recognition as the primary hormone that regulates the male skeleton. Estrogen in males is mainly derived from the conversion of testosterone to estradiol by the enzyme …
Baylor Role: Collaborator
Completed
Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants
Hypotension in the low birth weight (LBW) and extremely low birth weight (ELBW) infant is often encountered in the postnatal adaptation phase. Severe, prolonged hypotension contributes to cellular dysfunction and …
Baylor Role: Lead Sponsor
Completed
Radioactive Iodide Therapy for Pediatric Graves' Disease
Primary Aims. The investigators propose to assess the safety of 131I use in children with hyperthyroidism due to Graves' disease (GD). The investigators will measure whole body radiation exposure following …
Baylor Role: Collaborator
Completed
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients
The target fasting serum glucose (FSG) and pre-meal SG was 90-140 mg/dL, and the random SG was less than 180 mg/dL, taking into consideration the ADA/AACE target glucose levels in …
Baylor Role: Lead Sponsor
Completed
Intranasal Oxytocin and Maternal Neglect
The investigators plan to conduct fMRI scanning with a group of mothers who are blindly and randomly assigned either intranasal oxytocin or a placebo. Aim 1: To determine whether intranasal …
Baylor Role: Lead Sponsor
Terminated
Evaluating the Use of Exenatide in People With Type 2 Diabetes and Diastolic Heart Failure
Diastolic heart failure is a life-threatening condition that occurs when the ventricles of the heart become stiff and do not fully relax, preventing the heart from properly filling with blood. …
Baylor Role: Lead Sponsor
Completed
The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetes
A large study in people with type 2 diabetes (T2DM) showed that lowering blood sugars stopped or delayed the occurrence of health problems. As a result of the study, treatment …
Baylor Role: Lead Sponsor
Terminated
Testosterone for Penile Rehabilitation After Radical Prostatectomy
There was only one patient who began treatment with the study drug. After blind was broken, it was noted that he received placebo Testim and Viagra.
Completed
Understanding Sleep Problems in Children With Autism Spectrum Disorder
This is a proposal to study the relationship between melatonin (MT) and sleep problems in children with autism spectrum disorder (ASD), as part of the collaborative research structure of the …
Baylor Role: Lead Sponsor
Completed
Research Study for Children With Salt Wasting Congenital Adrenal Hyperplasia
The adrenal gland is a small organ of the body. It produces very important chemicals called hormones. One of these hormones, cortisol (the stress hormone) helps the body fight diseases. …
Baylor Role: Lead Sponsor