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Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
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Completed
A Trial Of Oral Chloral Hydrate Versus Intranasal Dexmedetomidine For Sedated Abr Exams (External Link)
The purpose of this study is to compare the efficacy of oral chloral hydrate to intranasal dexmedetomidine for the successful completion of a sedated ABR exam (hearing exam).
Baylor Role:
Lead Sponsor
Terminated
Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol (External Link)
Of the more than 1.5 million people who experience a traumatic brain injury (TBI) each year in the United States, as many as 75% sustain a mild TBI (MTBI) which …
Baylor Role:
Lead Sponsor
Completed
Investigation of Cycloserine as a Smoking Cessation Treatment (External Link)
See brief summary
Baylor Role:
Lead Sponsor
Withdrawn
Addition of Lactobacillus to Metronidazole in Treatment of CDAD (External Link)
Clostridium difficile associated disease (CDAD), which nearly always follows antibiotic therapy, has become increasingly common and important in American hospitals, causing substantial morbidity and mortality. Metronidazole is the recommended treatment …
Baylor Role:
Collaborator
Completed
Sequential and Hybrid Therapies for H Pylori Infection (External Link)
The purpose of this study is to test whether the 14-day sequential therapy ( esomeprazole plus amoxicillin dual therapy for 7 days followed by triple therapy with esomeprazole, clarithromycin, and …
Baylor Role:
Collaborator
Completed
Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection (External Link)
The purpose of this study is to compare different methods of giving combination drug therapy for treating Helicobacter pylori infection of the stomach. The entire study will last less than …
Baylor Role:
Collaborator
Completed
Research Study for Major Depressive Disorder: Investigation of Glutamate Medications (External Link)
This research proposal will investigate a glutamate-modulating agent, riluzole, in treatment-resistant patients who exhibit an acute, sustained response to a single dose of intravenous (IV) racemic ketamine. Fifty ketamine-responders will …
Baylor Role:
Lead Sponsor
Completed
Dietary Supplements for the Treatment of Angelman Syndrome (External Link)
AS is a neurologic disorder that may cause developmental delay, mental retardation, severe speech impairment, seizures, small head size, and problems with movement and balance in young children. AS is …
Baylor Role:
Collaborator
Unknown Status
Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions (External Link)
Candidates for bilateral carotid endarterectomy (CEA) who meet study criteria will provide informed consent before their randomization. Before the first CEA, the patient will have MRI, US, and EBCT exams …
Baylor Role:
Lead Sponsor
Completed
Dexmedetomidine in Pediatric Tonsillectomy (External Link)
Dexmedetomidine, an alpha 2 agonist provides some analgesia without respiratory depression. Children undergoing tonsillectomy and adenoidectomy occasionally have episodes of respiratory obstruction in the recovery room following administration of opioids. …
Baylor Role:
Lead Sponsor