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H-36731: Finasteride in Management of Elevated Red Blood Cells (External Link)
Hypogonadism is becoming an increasingly recognized clinical syndrome affecting millions of men in the United States and globally, and is characterized by symptoms including chronic fatigue, decreased libido and muscle …
Baylor Role:
Lead Sponsor
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Ticagrelor vs. Prasugrel Effects on Infarct Size (External Link)
Subjects and research staff (including the Magnetic Resonance Imaging (MRI) readers and interventional cardiologists) will not know what active treatment study drug the subjects are receiving. Study Arm 1: Ticagrelor …
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The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation (External Link)
Clopidogrel, ticagrelor and prasugrel are routinely used for platelet inhibition in addition to aspirin in patients after acute coronary syndromes. The platelet inhibition and patient outcomes (PLATO) trial showed that …
Baylor Role:
Lead Sponsor
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Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy (External Link)
ERCP with cholangioscopy is becoming a widespread technique to treat complicated choledocholithiasis, document CBD clearance after stone extraction and to assess biliary duct strictures. During the procedure, a large amount …
Baylor Role:
Lead Sponsor
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Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial (External Link)
Research Design and Methods: The study will be a multicenter, randomized, controlled, clinical trial comparing the anti-seizure effect of parenteral and/or oral labetalol (n = 4000) versus parenteral (intravenous or …
Baylor Role:
Lead Sponsor
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Acthar on Proteinuria in IgA Nephropathy Patients (External Link)
Participation in this study may last up to 2 years (from first visit to final visit) and includes 10 study visits and 8 phone calls. Subjects will be randomly assigned …
Baylor Role:
Lead Sponsor
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Androxal in Male Infertility (External Link)
It has been estimated that 4 to 5 million men in the United States are testosterone deficient, but fewer than 10% currently receive testosterone replacement therapy. There are many reasons …
Baylor Role:
Lead Sponsor
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Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS) (External Link)
The main study part has 3 phases. The first phase is called the baseline phase and consists of 1-2 study site visit(s). During this phase, the investigators will gather information …
Baylor Role:
Lead Sponsor
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Effect of Perioperative Intravenous Lidocaine on Postoperative Quality of Recovery in Patients Undergoing Spine Surgery (External Link)
Consented patients will be randomized to either saline group or lidocaine group. General anesthesia will be induced as it would normally be done in any patient undergoing spine surgery. Once …
Baylor Role:
Lead Sponsor
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Helicobacter Pylori and Body Iron in Adults (External Link)
This etiologic double-blind randomized trial in non-anemic mostly asymptomatic/mildly dyspeptic Hp-infected adults will assess whether Hp eradication results in improvements in the levels of iron stores. Iron stores will be …
Baylor Role:
Collaborator