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Recruiting
Standardized Prenatal Clinical Care for LUTO
Patients with LUTO will come for clinical evaluation as part of the standard clinical care at the our Fetal Center. The standardized prenatal management of plan for fetuses with LUTO …
Baylor Role: Lead Sponsor
Recruiting
New Pediatric Patching Method to Improve Compliance
Patients will present to the pediatric ophthalmology clinic at Texas Children's Hospital. If during the course of their standard care visit it is determined by their pediatric ophthalmologist or optometrist …
Baylor Role: Lead Sponsor
Recruiting
Sickle Cell Clinical Research and Intervention Program
The St. Jude Pediatric SCD Program has developed a comprehensive plan of care that spans the ages of 0 to 25, and provides the structure for screening and monitoring disease …
Baylor Role: Collaborator
Recruiting
Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)
Patients will give the investigators blood to make CD19 CD28 (with and without CD137) chimeric receptor-T cells in the laboratory. These cells will be grown and frozen. To make the …
Baylor Role: Lead Sponsor
Recruiting
High Resolution Microendoscopy for the Detection of Esophageal Squamous Cell Neoplasia
Our central hypothesis is that HRME can improve the efficiency and clinical impact of endoscopic screening and surveillance of esophageal squamous cell neoplasia by providing in-vivo optical biopsies comparable to …
Baylor Role: Collaborator
Recruiting
Natural History Study of GATA2 Deficiency and Related Disorders
Mutations in GATA2, a critical hematopoietic transcription factor, underlie a complex congenital disorder characterized by immunodeficiency, bone marrow failure, and lymphatic/vascular dysfunction. Patients with GATA2 deficiency may suffer from a …
Baylor Role: Collaborator
Recruiting
Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment
Study overview. This cross-sectional prospective observational study of patients with CoA previously treated using one of three treatment modalities assesses if treatment type is associated with differences in vascular function. …
Baylor Role: Collaborator
Recruiting
Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE
Subjects (or their syngeneic donor) will give blood for investigators to make EBV-specific (GRALE) T cells in the lab. These cells will be grown and frozen for the subject. The …
Baylor Role: Lead Sponsor
Recruiting
Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinoma
Primary outcomes: - the diagnostic yield (defined as the proportion of mucosal biopsy samples with neoplasia) of HRME with directed biopsy - compared to standard white-light endoscopy with 4-quadrant random …
Baylor Role: Collaborator
Recruiting
Monitoring Chronic Obstructive Pulmonary Disease Patients at Home by a Forced Oscillation Technique Device
The continuous progresses of medical science and technology and the improvement of life conditions have increased the life expectancy in industrialized countries: the result is the progressive population aging [UN, …
Baylor Role: Collaborator