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Search Clinical Trials
Recruiting
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism (External Link)
After age of 40, testosterone (T) production in men gradually decreases at a rate of 1.6% per year for total and to 2-3% per year for bioavailable T. This reduction …
Baylor Role:
Lead Sponsor
Recruiting
Glutathione in Mild Cognitive Impairment (External Link)
Subjects with MCI will be recruited by written informed consent using forms approved by the Baylor IRB. Subjects will stop nonvitamin supplements for 4wks before screening labs (blood count, HbA1c, …
Baylor Role:
Lead Sponsor
Recruiting
Bladder Tumor Biopsy Study to Improve Preoperative Determination of Stage and Grade (External Link)
Non-invasive bladder cancer is challenging to treat because it is a condition characterized by frequent recurrences that lead to numerous invasive procedures for detection and treatment. The mainstay of therapy …
Baylor Role:
Lead Sponsor
Recruiting
Mycobiome Evaluation in Children With Autism & GI Symptoms (External Link)
This study's primary aim is to explore the potential differences in the gut mycobiome of children with autism spectrum disorder compared to otherwise healthy children. The secondary objective of this …
Baylor Role:
Collaborator
Recruiting
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane (External Link)
The anesthetic potency of an inhalational anesthetic is measured by the minimum alveolar concentration (MAC), or the dose required to suppress movement to a surgical stimulus in 50% of patients. …
Baylor Role:
Lead Sponsor
Recruiting
GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma (External Link)
In this study the first step is to collect blood from the patient to make the GINAKIT cells. Once the GINAKIT cells are made they will be administered to the …
Baylor Role:
Lead Sponsor
Recruiting
HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM (External Link)
This is a prospective phase I-II study to assess the efficacy and toxicity of HSV-tk + valacyclovir gene therapy in combination with radiotherapy in recurrent glioblastoma multiforme or anaplastic astrocytoma. …
Recruiting
Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen (External Link)
To make the T cells the investigators will take blood from the patient or from the previous bone marrow transplant donor and stimulate it with growth factors to make the …
Baylor Role:
Lead Sponsor
Recruiting
Effects of Transitional Circulation in ELBW Infants (External Link)
Screening Phase: The subject's parents/guardians/LAR will be approached if the infant's birth weight makes them eligible for this research study. Study Phase: During this study, we will use the monitoring …
Baylor Role:
Lead Sponsor
Recruiting
Early Predictors of Necrotizing Enterocolitis in Neonates (External Link)
The study will enroll premature, low birth weight infants in the Neonatal Intensive Care Units (NICU). Potential study subjects will be identified upon delivery, or transfer to the NICU, and …
Baylor Role:
Lead Sponsor