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Recruiting
Continuous Diffusion of Oxygen Treatment for Incision Wounds
Surgical wound complications such as infection, dehiscence, necrotic tissue, surgical revision, and poor cosmesis are unfortunately highly prevalent in patients post breast reconstruction. In particular, necrosis/ischemia post breast reconstruction because …
Baylor Role: Lead Sponsor
Recruiting
Understanding Prefrontal and Medial Temporal Neuronal Responses to Algorithmic Cognitive Variables in Epilepsy Patients
Humans have a remarkable ability to flexibly interact with the environment. A compelling demonstration of this cognitive flexibility is human's ability to respond correctly to novel contextual situations on the …
Baylor Role: Lead Sponsor
Recruiting
Uterine Manipulation During Minimally Invasive Surgery for Early Stage Endometrial Cancer
In most cases, patients who have early stage endometrial cancer undergo a surgery to remove the uterus, cervix, tubes, ovaries, and occasionally lymph nodes. This is usually done through a …
Recruiting
Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors
The growing prevalence of obesity in older adults including many older Veterans, has become a major concern in the US already strained health care system in general and in the …
Baylor Role: Collaborator
Recruiting
Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
Improving healthy habits such as sleep, nutrition or physical activity is expected to enhance rehabilitation in knee or hip arthroplasty patients, by increasing their ability to attend and adhere to …
Baylor Role: Lead Sponsor
Recruiting
L-Citrulline Dose Finding Safety Study in MELAS
The human body is made of many cells and each cell contains many mitochondria. Mitochondria are called the powerhouses of the cell, because they produce the energy needed for a …
Baylor Role: Lead Sponsor
Recruiting
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders
Histiocytic disorders are diseases caused by misfunctioning or buildup of particular immune cells called histiocytes. Many histiocytic disorders (LCH, juvenile xanthogranuloma (JXG), Erdheim-Chester disease (ECD), and Rosai-Dorfman Disease (RDD)) arises …
Baylor Role: Collaborator
Recruiting
TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.
The virus-specific T cells (VSTs) given to the patient will be thawed and injected into their intravenous line. To prevent an allergic reaction if the patient had a prior reaction …
Baylor Role: Lead Sponsor
Recruiting
Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity
This study aims to evaluate the effects of oral glycine supplementation on plasma glycine concentration, intracellular glutathione (GSH) concentration, plasma acylglycine concentration, urine acylglycine concentration, and insulin resistance in subjects …
Baylor Role: Collaborator
Recruiting
Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population
Transitioning from busulfan, hydroxyurea, IFN-α to tyrosine kinase inhibitors (TKIs) has dramatically altered the natural history of CML. Patients with CML appropriately managed with TKIs are able to benefit from …
Baylor Role: Lead Sponsor