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120 Results
Completed
The Effect of Diet and Exercise in Heart Failure
A growing number of people in this country are overweight or obese. This is concerning as increasing weight has been shown to increase the risk of developing heart failure. However, …
Baylor Role: Lead Sponsor
Completed
Lantus in the Treatment of Type 1 Diabetes Children
The landmark report of the diabetes control and complications trial (DCCT) trial has shown that intensive management delays and/or prevents complications in small vessels associated with Type 1 diabetes (T1DM). …
Baylor Role: Lead Sponsor
Completed
Ability to Cope With Type 1 Diabetes
Coping with type 1 diabetes can be very difficult. Type 1 diabetes is a very unique chronic disease because it requires constant attention to several responsibilities such as daily glucose …
Baylor Role: Lead Sponsor
Completed
Ability to Cope With Type 1 Diabetes
Coping with type 1 diabetes can be very difficult. Type 1 diabetes is a very unique chronic disease because it requires constant attention to several responsibilities such as daily glucose …
Baylor Role: Lead Sponsor
Completed
Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia
BACKGROUND: HIV lipodystrophy syndrome is associated with both metabolic (e.g., dyslipidemia and insulin resistance) and anthropomorphic (e.g., lipoatrophy and central obesity) abnormalities. These defects are likely to predispose HIV patients …
Baylor Role: Lead Sponsor
Completed
The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes
The Diabetes Control and Complications Trial (DCCT) showed that improving blood sugar control for individuals with Type 1 diabetes (T1DM) stopped or delayed the onset of long-term complications. As a …
Baylor Role: Lead Sponsor
Completed
Study of Antioxidants and Oxidants in Malnourished Children
It is believed that the organs of severely malnourished children malfunction because harmful compounds called oxidants injure the tissues in these organs. In a healthy person oxidants are made harmless …
Baylor Role: Lead Sponsor
Completed
Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy Syndrome
The HIV lipodystrophy syndrome (HLS) is characterized by peripheral fat wasting and central obesity, and hyperlipidemia (mainly hypertriglyceridemia), which results in insulin resistance. HLS patients are at high risk for …
Baylor Role: Lead Sponsor
Completed
The Role of Amylin and Glucagon in T1DM
Objective: To develop a new treatment approach in the prevention of hypo and hyperglycemia in children with type 1diabetes. Background/Rationale: The diabetes control and complications trial (DCCT) showed that improving …
Baylor Role: Lead Sponsor
Terminated
Monoclonal Antibody Conditioning for Allogeneic Stem Cell Transplantation of Patients With Inherited Metabolic Storage Diseases
Fludarabine will be given as a daily IV (intravenous, by vein) infusion for a total of 5 days. CAMPATH-1H will be given as a daily 4-hour IV (intravenous, by vein) …
Baylor Role: Lead Sponsor