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Recruiting
XEN1101 for Major Depressive Disorder (External Link)
This project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the KCNQ-selective channel opener XEN1101 …
Baylor Role: Collaborator
Recruiting
Acute Modulation of Stereotyped High-Frequency Oscillations (External Link)
High-frequency oscillations (HFOs) of intracranial EEG (iEEG) have the potential to identify the surgical resection area/seizure onset zone (SOZ) in patients with drug-resistant epilepsy. However, multiple reports indicate that HFOs …
Baylor Role: Collaborator
Recruiting
Utility of Advanced Ultrasound Otoscope In The Diagnosis of AOM (External Link)
The objective of this study is to collect ultrasound signal information and visual otoscopic images with an engineering prototype device for children scheduled for tympanostomy tube surgery for the purpose …
Baylor Role: Lead Sponsor
Recruiting
SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs (External Link)
An estimated 8 million individuals in America are affected by peripheral arterial disease (PAD). One of its extreme expressions is Critical Limb Ischemia (CLI). It is one of the most …
Baylor Role: Collaborator
Recruiting
Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells (External Link)
To make the T cells, the investigators will take the patient's blood and stimulate it with growth factors to make the T cells grow. To get the CD7 antibody and …
Baylor Role: Lead Sponsor
Recruiting
Exploring the Effects of Spinal Cord Stimulation in Parkinson's Disease. (External Link)
Freezing of gait (FOG) is a devastating motor phenomenon which may occur in patients with Parkinson's Disease (PD) and other neurodegenerative disorders. It is characterized by episodes during which patients …
Recruiting
Micro-hematology Analyzer for Viral/Bacterial Description (External Link)
The purpose of the study is to evaluate the reliability and accuracy of a newly developed point-of-care analyzer, the CytoTracker, to measure complete blood count (CBC) parameters. The CytoTracker results …
Baylor Role: Collaborator
Recruiting
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes (External Link)
Type 2 diabetes is an increasingly common disease that affects more than 10 percent of adults in the United States. Multiple medications are available to treat this condition. However, many …
Baylor Role: Collaborator
Recruiting
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors (External Link)
Approximately 118-27 subjects will participate in the treatment part of this study. Maximum of 180 mL of blood (approximately 12 tablespoons) is collected from patients to grow the T cells …
Baylor Role: Lead Sponsor
Recruiting
BiZact Tonsillectomy in the Pediatric Population (External Link)
Tonsillectomy is the second most common pediatric surgical procedure, with more than 280,000 performed in children under the age of 15 in the United States in 2010. The most common …
Baylor Role: Lead Sponsor