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Completed
Clinical Trial of Wireless CranioFacial Nerve Stimulation (CFNS) for the Treatment of CranioFacial Neuropathic Pain (External Link)
Subjects will be randomized at enrollment into either a delayed or immediate continuation group. The immediate continuation group will immediately continue with the stimulation after a 30-day trial period and …
Baylor Role: Collaborator
Completed
Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma (External Link)
Information from laboratory studies and retrospective studies of patients with this disease has shown that the addition of metformin (a commonly used medicine for treating diabetes) to chemotherapy and radiation …
Baylor Role: Lead Sponsor
Completed
Automated Fetal Weight Estimation: A Multicenter Validation Using Fractional Limb Volume (External Link)
Ultrasound has been used for over 20 years to estimate fetal weight prior to birth. Sometimes this estimation is not always similar to what the baby actually weighs. In addition …
Baylor Role: Lead Sponsor
Completed
'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial (External Link)
This is a multi-center, non-blinded randomized controlled trial in fetuses with isolated moderate CDH, i.e. moderate lung hypoplasia (as determined by prenatal assessment of lung development). It essentially compares fetal …
Baylor Role: Collaborator
Completed
Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children (External Link)
Double blind, randomized, controlled, dose-escalation Phase 1 clinical trial in hookworm-exposed children aged 6 to 10 years living in the area of Lambaréné, Gabon. Children will receive three doses of …
Baylor Role: Lead Sponsor
Completed
Gravity Assisted Technique for Esophageal Endoscopic Submucosal Dissection (ESD) (External Link)
Early precancerous esophageal lesions and esophageal cancer, are a threatening illnesses with high mortality rate, so the early intervention is critical during the course of treatment, statistically, every year an …
Baylor Role: Lead Sponsor
Completed
An Innovative Virtually Supervised Exercise for Dialysis Patients (External Link)
Among patients with diabetes 35% suffer from chronic renal disease and may require dialysis or kidney replacement over time. Furthermore, in diabetics with end stage renal disease (ESRD) that require …
Baylor Role: Lead Sponsor
Completed
Prefrontal Cortical Engagement Through Non-Invasive Brain Stimulation in Schizophrenia (External Link)
Cognitive deficits are a strong predictor of functional outcome in schizophrenia, yet poorly remediated by current treatments. Disturbances in dorsolateral prefrontal cortex (DLPFC) function underlie core impairments such as in …
Baylor Role: Lead Sponsor
Completed
Home Away From Home - Quality of Life Surveys (External Link)
This is a prospective observational cohort study, where the primary objective of this study is to compare patient and caregiver quality of life and other patient-centered outcomes for inpatient versus …
Baylor Role: Collaborator
Completed
Overcoming Obstacles in Epigenetic Analysis of Human Twins (External Link)
Cardiovascular disease (CVD) is the leading cause of death in the US, emphasizing an incomplete understanding of its pathology and translation into effective interventions. The fetal origins hypothesis posits that …
Baylor Role: Lead Sponsor