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Completed
Study to Treat Major Depressive Disorder With a New Medication (External Link)
Depressive disorders are among the most disabling medical conditions worldwide and currently available treatments fall short of addressing this large public health burden. Dysfunction within the brain reward system is …
Baylor Role: Collaborator
Completed
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD (External Link)
Argininosuccinate lyase deficiency (ASLD; also known as argininosuccinic aciduria) is the second most common urea cycle disorder (UCD) and accounts for 15-20% of all disorders of ureagenesis. Individuals with ASLD …
Baylor Role: Lead Sponsor
Completed
Online Videos and New Feeding Content to Enhance a Current EFNEP Program (External Link)
During Phase I of the project (first two years), the leadership team composed of both research and extension investigators will work with the media production team to edit the SEEDS …
Baylor Role: Lead Sponsor
Completed
Long-term Lifestyle Change and Testosterone Replacement (External Link)
Background: There are studies on long-term testosterone replacement in older adults with hypogonadism showing benefits on body composition, sexual function and mood but not on testosterone replacement therapy in combination …
Baylor Role: Lead Sponsor
Completed
Strengths-Based Behavioral mHealth App for Parents of Adolescents With Type 1 Diabetes-Pilot Study (External Link)
Type 1 diabetes (T1D) is among the most common chronic conditions of childhood and its management is complex and relentless. Adolescents have increased risk for worsening glycemic control, putting them …
Baylor Role: Lead Sponsor
Completed
Mirabegron as Medical Expulsive Therapy (MET) for Ureteral Stones and Ureteral Stent Pain (External Link)
The study will be a prospective randomized double-blind placebo-controlled trial of mirabegron for medical expulsive therapy (MET) in patients with a CT scan-proven ureteral stone between 4 to 10 mm …
Baylor Role: Lead Sponsor
Completed
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial (External Link)
Youth between the ages of 13 and 24 accounted for 22% of all new HIV infections in 2015. Less than half (44%) of youth living with HIV (YLWH) in the …
Baylor Role: Collaborator
Completed
Micro-mobile Foot Compression and Diabetic Foot (External Link)
Diabetic foot ulceration (DFU) is a common and largely preventable complication. While most of these ulcers can be treated successfully, some will persist and become infected. Ultimately, nearly one fifth …
Baylor Role: Lead Sponsor
Completed
Metabolomics for Biomarker Discovery in Children With EoE (External Link)
Eosinophilic esophagitis (EoE) is a disorder of the esophagus triggered by food and/or environmental allergens and is characterized by symptoms of esophageal dysfunction and eosinophilia of the esophagus. The standard …
Baylor Role: Collaborator
Completed
Fetal Hemoglobin Induction Treatment Metformin (External Link)
This is a dose escalation, pilot study for subjects with sickle cell anemia (SCA) disease to determine if metformin has a beneficial effect on the treatment and quality of life …
Baylor Role: Lead Sponsor