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Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT) (External Link)
Veterans with Gulf War Illness (GWI) often experience a range of debilitating symptoms, including fatigue, chronic pain, depression, anxiety, and cognitive dysfunction. The factors contributing to these symptoms remain poorly …
Baylor Role:
Lead Sponsor
Recruiting
EVD Drainage Data and Intracranial Pressure (ICP) Measurements (External Link)
Hydrocephalus is caused by excess cerebrospinal fluid in the brain that can lead to lethargy, seizures, and comas. There is no cure for it nor is there any way to …
Baylor Role:
Lead Sponsor
Recruiting
Intracranial Investigation of Neural Circuity Underlying Human Mood (External Link)
Depression is one of the most common disorders of mental health, affecting 7-8% of the population and causing tremendous disability to afflicted individuals and economic burden to society. In order …
Baylor Role:
Lead Sponsor
Recruiting
Systematic Light Exposure in Pediatric Brain Tumor Survivors (External Link)
Participants will be randomized to take part in one of two groups: 1. The Bright Light Group will be exposed to bright light (1,000 lux at eye level) using light …
Baylor Role:
Lead Sponsor
Recruiting
Hepatic Histopathology in Urea Cycle Disorders (External Link)
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism. With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this …
Baylor Role:
Lead Sponsor
Recruiting
Platelet Function in Patients With Ischemic Stroke Treated With Anti-thrombotic or Thrombolytic (External Link)
In the past we used 30% lower dose of abciximab compared to the cardiac trials and the discontinued ABESTT stroke trial. There were no symptomatic intracranial hemorrhages or thromboyctopenia in …
Baylor Role:
Lead Sponsor
Recruiting
Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease (External Link)
Glutathione (GSH) deficiency, oxidative stress, mitochondrial dysfunction, insulin resistance and inflammation are linked to Alzheimer's disease (AD). In prior studies, investigators have shown that GSH deficiency contributes to mitochondrial impairment …
Baylor Role:
Lead Sponsor
Recruiting
Liver Disease in Urea Cycle Disorders (External Link)
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism. With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this …
Baylor Role:
Lead Sponsor
Recruiting
Care Coordination System for People With Dementia (External Link)
In this study the investigator will assess the effectiveness of a care coordination device (a supportive care device) called, Care4AD for reducing burden and stress of caregivers, enhancing patient adherence …
Recruiting
Acute Modulation of Stereotyped High-Frequency Oscillations (External Link)
High-frequency oscillations (HFOs) of intracranial EEG (iEEG) have the potential to identify the surgical resection area/seizure onset zone (SOZ) in patients with drug-resistant epilepsy. However, multiple reports indicate that HFOs …
Baylor Role:
Collaborator