MicroRNA Biogenesis Proteins: From Ontogenesis to Oncogenesis
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This Precision Medicine Grand Rounds session will take place on Thursday, January 12, 2023 at 12:00 p.m. Live attendance will be available virtually through Zoom.
Activity Information
Needs Statement
Most medical professionals have insufficient knowledge about the role that precision medicine has in clinical practice. Genetic alterations affect all types of cancer and often affect cardiovascular, autoimmune, and neurological diseases. Laboratory tools used in precision medicine are highly sophisticated and include genomics, proteomics, and other high-dimensional assays. The series will provide regular updates on these tools, the ways the tools could improve patient care, and the ethical and legal issues surrounding genetic testing. The series will also examine how testing for genetically influenced diseases can affect personalized management of individuals and their families.
Educational Objectives
At the conclusion of the session, the participants should be able to:
- Summarize and discuss the basics of RNA interference, the structure and function of microRNAs, and the key elements of microRNA biogenesis.
- Distinguish between the clinical syndromes associated with pathogenic variants in the miRNA biogenesis proteins.
- Identify the similarities and differences between different DICER1-related tumors.
Target Audience
Professional Categories
- Physicians
- Medical Students
- Fellows
- Nurses
- Other Health Professionals
Specialties
- Medical Genetics and Genomics
Interest Groups
- Hospital Medicine
Accreditation/Credit Designation
Baylor College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Baylor College of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Activity Director
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Christopher Amos, Ph.D.
Director for the Institute of Clinical and Translational Medicine
Baylor College of Medicine
Disclosure Policy
Baylor College of Medicine (BCM) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians. BCM is committed to sponsoring CE activities that are scientifically based, accurate, current, and objectively presented.
In accordance with the ACCME Standards for Commercial Support, BCM has implemented a mechanism requiring everyone in a position to control the content of an educational activity (i.e., directors, planning committee members, faculty) to disclose any relevant financial relationships with commercial interests (drug/device companies) and manage/resolve any conflicts of interest prior to the activity. Individuals must disclose to participants the existence or non-existence of financial relationships at the time of the activity or within 24 months prior.
In addition, BCM has requested activity faculty/presenters to disclose to participants any unlabeled use or investigational use of pharmaceutical/device products; to use scientific or generic names (not trade names) in referring to products; and, if necessary to use a trade name, to use the names of similar products or those within a class. Faculty/presenters have also been requested to adhere to the ACCME's validation of clinical content statements.
BCM does not view the existence of financial relationships with commercial interests as implying bias or decreasing the value of a presentation. It is up to participants to determine whether the relationships influence the activity faculty with regard to exposition or conclusions. If at any time during this activity you feel that there has been commercial/promotional bias, notify the Activity Director or Activity Coordinator. Please answer the questions about balance and objectivity in the activity evaluation candidly.
All of the relevant financial relationships listed for these individuals have been mitigated.
Disclosures
The following individual(s) has/have reported financial or other relationship(s) with commercial entities whose products/services may relate to the educational content of this activity:
Presenter
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William Foulkes, M.B.B.S., Ph.D., FRCPC
Professor of Oncology, Medicine and Human Genetics
James McGill University
Disclosure:
Nothing to disclose.
Activity Director
-
Christopher Amos, Ph.D.
Director for the Institute of Clinical and Translational Medicine
Baylor College of Medicine
Disclosure:
Nothing to disclose.
Planning Committee Members
-
Christopher Amos, Ph.D.
Director for the Institute of Clinical and Translational Medicine
Baylor College of Medicine
Disclosure:
Nothing to disclose.
-
-
Richard A. Gibbs, Ph.D.
Wofford Cain Chair and Professor, Director of the Baylor College of Medicine Human Genome Sequencing Center
Baylor College of Medicine
Disclosure:
Nothing to disclose.
-
Bo Peng, Ph.D.
Associate Professor of Medicine, Epidemiology and Population Science
Baylor College of Medicine
Disclosure:
Nothing to disclose.
-
Rowland Pettit, Ph.D.
Medical Scientist Training Program (MD/PhD)
Baylor College of Medicine
Disclosure:
Nothing to disclose.
Health Topics
Presenter:
