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53 Results
Recruiting
Causal Mechanisms in Adolescent Arterial Stiffness
Aortic stiffness measured in adolescence or adulthood determines current hypertension, predicts future incidence of hypertension, and future atherosclerotic cardiovascular disease (ASCVD) events. International hypertension guidelines list severe aortic stiffness as …
Baylor Role: Lead Sponsor
Completed
Feasibility Study of Family Teamwork Peer-Delivery
The purpose of this study is to 1) convene African American and Latino Community Coalitions to adapt Family Teamwork (FT) for school-age youth, and integrate FT with the Smart and …
Baylor Role: Lead Sponsor
Completed
Obesity-Related Glycine Deficiency: Investigating a Long-standing Metabolic Paradox Using Bedside and Bench Approaches
Metabolic tracers: 1,2-[13C2]-Glycine, 1,2-[13C2]-Glycine, 2,3,3,-[2H3]-Serine and [2H5]-Phenylalanine will be infused for quantification of various pathways associated with glycine metabolism.
Baylor Role: Collaborator
Completed
Study of Arginine and Nitric Oxide in Patients With Diabetes
Both arginine and its derivative nitric oxide (NO) have been implicated in the regulation of glucose homeostasis. Arginine is a β cell secretagogue, potentiating glucose stimulated insulin secretion. Further, it …
Baylor Role: Lead Sponsor
Terminated
Coaching and Education for Diabetes Distress
Diabetes distress (DD) is a negative emotional reaction to a diagnosis of diabetes and concerns about the burden of managing diabetes, the risk of complications, and inadequate support system. DD …
Baylor Role: Lead Sponsor
Completed
Technology to Improve the Health of Resource-poor Hispanics With Diabetes
The number of Hispanics diagnosed with diabetes is escalating in the US with disproportionately higher prevalence and complication rates than other ethnicities. CHWs are a well-established and culturally sensitive means …
Baylor Role: Lead Sponsor
Completed
Strengths-Based Behavioral mHealth App for Parents of Adolescents With Type 1 Diabetes-Pilot Study
Type 1 diabetes (T1D) is among the most common chronic conditions of childhood and its management is complex and relentless. Adolescents have increased risk for worsening glycemic control, putting them …
Baylor Role: Lead Sponsor
Completed
Effects of Diet Interventions on Monocytes in Metabolic Syndrome
Subjects with hypertriglyceridemia and metabolic syndrome are being recruited and receive diet interventions with either a high-saturated fat diet or a low-fat high protein diet for 4 days (days 1-4) …
Baylor Role: Lead Sponsor
Completed
First STEPS- Study of Type 1 in Early Childhood and Parenting Support
Research Design and Methods Overview of Study Design & Procedure. The aim of this randomized controlled trial (RCT) is to determine the efficacy of a stepped care intervention that provides …
Baylor Role: Collaborator
Terminated
Effect of Dapagliflozin on Inflammation and Endothelial Function
The insulin-resistant state of type 2 diabetes mellitus (T2DM) is largely mediated by inflammatory pathways affecting skeletal muscle which is the primary site of whole body insulin resistance. Nuclear factor …
Baylor Role: Lead Sponsor