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4 Results
Completed
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
The noradrenergic system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. Doxazosin is a long-acting and selective alpha 1-adrenergic receptor blocker, which inhibits …
Baylor Role: Collaborator
Completed
Bicuspid Valve Aortopathy Feasibility Study
The study will consider all patients with a bicuspid aortic valve and 1) determine the number of patients needed to be screened for a clinical trial, based on patient eligibility …
Baylor Role: Collaborator
Completed
The Efficacy of Doxazosin for Cocaine Users
The NE system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. The results of this study will provide medical safety data on the …
Baylor Role: Lead Sponsor
Completed
Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts
Heroin addiction is a serious health problem with no available medical treatment for preventing relapse. Naltrexone is a medication that is currently used to treat substance addiction. It acts by …
Baylor Role: Lead Sponsor