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Withdrawn
Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg
The purpose is to find out if the addition of dexamethasone to ropivacaine 0.5% increases the duration of pain relief provided by popliteal sciatic nerve block performed for foot/ankle surgery. …
Baylor Role: Lead Sponsor
Withdrawn
Efficacy of Gabapentin in Prevention of Tourniquet Pain and Hypertension
The purpose of the study is to find out if taking a dose of gabapentin 600 mg by mouth (po) before surgery will help prevent the development of tourniquet pain …
Baylor Role: Lead Sponsor
Withdrawn
Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Men who participate in this study will take both metformin and simvastatin every day. Both drugs are pills and can be taken at home. Subjects will be asked to take …
Withdrawn
Umbilical Cord Blood Transplant for Children With Lymphoid Hematological Malignancies
After the eligible criterion for treatment has been met and a suitable UCB stem donor has been found, the patient will have a central line placed. Research Therapy: After placement …
Baylor Role: Lead Sponsor
Withdrawn
RTI-336 as a Treatment for Methamphetamine Dependence
Methamphetamine (METH) is a highly addictive stimulant and acute exposure causes dopamine (DA) release and stimulates midbrain reward centers. The proposed work represents an important research effort with considerable public …
Baylor Role: Lead Sponsor
Withdrawn
A Study of Bevacizumab to Prevent Malignant Ascites
All subjects will be treated with an intravenous infusion of the experimental drug (Bevacizumab 15 mg/kg) every 3 weeks for a total of twelve (12) weeks on study. The primary …
Baylor Role: Lead Sponsor
Withdrawn
Addition of Lactobacillus to Metronidazole in Treatment of CDAD
Clostridium difficile associated disease (CDAD), which nearly always follows antibiotic therapy, has become increasingly common and important in American hospitals, causing substantial morbidity and mortality. Metronidazole is the recommended treatment …
Baylor Role: Collaborator
Withdrawn
Varenicline-Methamphetamine Interaction Study (2008)
See Brief Summary
Baylor Role: Lead Sponsor
Withdrawn
Study of LMP1- and LMP2- Specific Cytotoxic T-Lymphocytes (CTL)
While patients with nasopharyngeal carcinoma (NPC) may be cured by chemotherapy and radiotherapy, the outlook for patients who are resistant to this treatment or who relapse is poor. Almost all …
Baylor Role: Lead Sponsor
Withdrawn
Rituximab for GVHD
Acute graft-versus-host disease (aGVHD), one of the most important complications of allogeneic hematopoietic stem cell transplantation (HSCT) is associated with significant morbidity and mortality. Grades II to IV aGVHD occur …
Baylor Role: Lead Sponsor