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Imaging-Guided Low Intensity Focused Ultrasound (LIFU) (External Link)
The current project will investigate a novel neurostimulation approach, low intensity focused ultrasound (LIFU), which combines non-invasiveness and a sharp spatial focus in deep brain regions. This open-label early feasibility …
Baylor Role:
Lead Sponsor
Recruiting
Genetic Inclusion by Virtual Evaluation (External Link)
Inadequate access to genetics evaluation and genomic testing in the Hispanic minorities living along the Texas-Mexico has marginalized the most vulnerable pediatric group. In this study, we will (1) implement …
Baylor Role:
Lead Sponsor
Recruiting
Expanding Reach of Evidence-based Psychotherapy for Veterans With Co-occurring Anxiety and Substance Use Disorders. (External Link)
The current study seeks to better understand how to improve access to evidence-based psychotherapy (EBP) for rural Veterans with co-occurring anxiety and substance use disorders (SUD) using a web-based cognitive …
Baylor Role:
Lead Sponsor
Recruiting
Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing (External Link)
The overall goal of this study is to map the spatiotemporal dynamics of social affective processing and to examine selective modulation of these dynamics in humans undergoing invasive intracranial monitoring …
Baylor Role:
Lead Sponsor
Recruiting
Electrical Stimulation for Post Acute COVID-19 Syndrome (External Link)
Postacute COVID-19 syndrome (PACS) is an emerging entity that has been clearly recognized by musculoskeletal pain, fatigue, cognitive, and sleep disturbances, among other symptoms, in patients who have recovered from …
Baylor Role:
Lead Sponsor
Recruiting
Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease (External Link)
Glutathione (GSH) deficiency, oxidative stress, mitochondrial dysfunction, insulin resistance and inflammation are linked to Alzheimer's disease (AD). In prior studies, investigators have shown that GSH deficiency contributes to mitochondrial impairment …
Baylor Role:
Lead Sponsor
Recruiting
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users (External Link)
The OFC is functionally connected to other cortical brain regions (e.g., prefrontal and parietal cortices) but also subcortical areas in the dorsal striatum, a core reward circuitry region. The functional …
Baylor Role:
Lead Sponsor
Recruiting
Care Coordination System for People With Dementia (External Link)
In this study the investigator will assess the effectiveness of a care coordination device (a supportive care device) called, Care4AD for reducing burden and stress of caregivers, enhancing patient adherence …
Recruiting
Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression (External Link)
Depression and falls are significantly higher in low-income, racially diverse homebound seniors than in the general older-adult population; however, the existing systems of care are not equipped to address disparities …
Baylor Role:
Collaborator
Recruiting
XEN1101 for Major Depressive Disorder (External Link)
This project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the KCNQ-selective channel opener XEN1101 …
Baylor Role:
Collaborator