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Recruiting
The Effect of Fluids on Aortic VTI During C-section
Pregnancy is associated with a myriad of physiologic changes, including expansion of blood volume, decrease in oncotic pressure, and increased cardiac output. Comorbidities including maternal hypertension, renal or cardiac disease …
Baylor Role: Lead Sponsor
Recruiting
Causal Mechanisms in Adolescent Arterial Stiffness
Aortic stiffness measured in adolescence or adulthood determines current hypertension, predicts future incidence of hypertension, and future atherosclerotic cardiovascular disease (ASCVD) events. International hypertension guidelines list severe aortic stiffness as …
Baylor Role: Lead Sponsor
Recruiting
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome
Investigators will measure pre-determined biomarkers with known or suspected association with ARDS severity or outcome. Simultaneously, investigators will measure gene expression of peripheral blood. Both plasma biomarkers and gene expression …
Baylor Role: Collaborator
Recruiting
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
The investigators are conducting a natural history study of patients with congenital disorders of glycosylation (CDG). The study will look into the progression of the disease amongst the participants and …
Baylor Role: Collaborator
Recruiting
Preventing Persistent Post-Surgical Pain and Dysfunction
Persistent post-surgical pain (PPSP) is a common and debilitating problem following surgery.1 Orthopedic surgeries, such as Total Knee Arthoplasty (TKA), are consistently associated with high postoperative pain, putting patients at …
Baylor Role: Collaborator
Recruiting
High Dose Albumin in Refractory Ascites
Patients with advanced liver disease often has low serum albumin level. The Infusion of human albumin is a standard of care after removal of ascitic fluid in patients with cirrhosis …
Baylor Role: Lead Sponsor
Recruiting
Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program?
AIM 1: We will categorize children ages 7-12 yrs. of age with FGIDs (n=250) as to whether they have/do not have one or more of the following abnormal physiologic changes: …
Baylor Role: Lead Sponsor
Recruiting
Reading Remediation and Outcomes in Detention
Learning disabilities (LD) are among the most common types of disabilities in juvenile offenders that have been linked to delinquency. Nationwide, children and youth with special education needs are overrepresented …
Baylor Role: Lead Sponsor
Recruiting
Pediatric Acute Gastrointestinal Bleeding Registry
A. Specific Aims/Objectives: The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding. This is defined as bleeding …
Baylor Role: Collaborator
Recruiting
Bladder Directed vs. Pelvic Floor Therapy in IC/BPS
This will be a prospective randomized trial of pelvic floor therapy vs. bladder directed therapy. The study target population consists of females, aged 18 to 85 years of age with …
Baylor Role: Collaborator