Seth Paul Lerner, M.D., FACS Photo

Seth Paul Lerner, M.D., FACS

Baylor College of Medicine


Baylor College of Medicine
Houston, TX US


Baylor College of Medicine Medical Center (Work)
7200 Cambridge, Room A10.107
Mail Stop: BCM380
Houston, Texas 77030
United States
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Baylor College of Medicine Medical Center (Clinic)
7200 Cambridge, Suite 10B
Houston, Texas 77030
United States
(713) 798-4001
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  • American Board of Urology


  • B.A. from University Of Texas At Austin
    01/1979 - Austin, TX United States
  • M.D. from Baylor College Of Medicine
    01/1984 - Houston, TX United States
  • Internship at Virginia Mason Hospital
    01/1985 - Seattle, Washington United States
  • Residency at Virginia Mason Hospital
    06/1986 - Seattle, Washington United States

  • Residency at Baylor College of Medicine
    06/1990 - Houston, Texas United States

  • Fellowship at University Of Southern California
    06/1992 - Los Angeles, California United States


  • English


  • Male

Professional Statement

Seth P. Lerner, MD, is Professor of Urology and holds the Beth and Dave Swalm Chair in Urologic Oncology, in the Scott Department of Urology, Baylor College of Medicine. He is Director of Urologic Oncology and the Multidisciplinary Bladder Cancer Program and Faculty Group Practice Medical Director for the Urology Clinic. He earned his medical degree from Baylor College of Medicine, completed a surgical internship at Virginia Mason Hospital in Seattle, and returned to Baylor for his residency training. He completed a two-year fellowship at the University of Southern California in urologic oncology and reconstructive surgery under Peter Jones and Don Skinner before returning to join the full-time Baylor faculty in 1992. His clinical practice, education, and research activities are devoted to urologic oncology and particularly lower and upper tract urothelial cancer. Dr. Lerner is author of over190 peer-reviewed articles, and co-editor of a comprehensive Textbook of Bladder Cancer. He is the founding co-editor-in-chief of the Bladder Cancer journal. He established and directs the multi-disciplinary Bladder Cancer Research Program at Baylor and his research interests include use of selective estrogen receptor modulators for treatment of bladder cancer, gene therapy, integrated genomic analysis of bladder and upper urinary tract cancers, and outcomes of radical cystectomy and pelvic lymphadenectomy. He has 26 years experience as a clinical investigator for both NCI and industry funded clinical trials. He is the PI of the ongoing SWOG NCI Phase III trial comparing extended vs. standard pelvic lymphadenectomy at time of radical cystectomy. He is active in the leadership of several national bladder cancer research enterprises including chair of the Local Bladder Cancer committee of SWOG, founding and former co-chair of the NCI Bladder Cancer Task Force and current co-chair of the NCI CTEP Genitourinary Steering Committee, and he has co-chaired the Analysis Working Group of The Cancer Genome Atlas Project for muscle invasive bladder cancer for the past 7 years. He is very active in the Bladder Cancer Advocacy Network (BCAN) as a member of the Board of Directors, past chair of the Bladder Cancer Think Tank and co-chair of the management committee of the Bladder Cancer Research Network. Dr. Lerner is an active member of the prestigious American Association of Genitourinary Surgeons and is listed routinely among “America’s Top Doctors” and “Best Doctors in America.

Professional Interests

  • Urologic Oncology and Reconstructive Surgery with Interest in Minimally Invasive Surgery

Physician Specialties

  • Urology


  • American Association of Genitourinary Surgeons
  • Harris County Medical Society
  • International Bladder Cancer Network
  • Society of Basic Urologic Research
  • Société International D’Urologie
  • Society of Laparoendoscopic Surgeons
  • South Central Section of the American Urological Association
  • Society of University Urologists
  • Southwest Oncology Group
  • Texas Urological Society
  • Texas Medical Association
  • American Urological Association
  • American Association for Cancer Research
  • American Association for the Advancement of Science
  • American College of Surgeons
  • American Medical Association
  • American Society of Clinical Oncology
  • American Society of Gene Therapy
  • American Association of Clinical Urologists