Detecting and Targeting Endothelial Dysfunction in Preeclampsia: Molecular Mechanisms and Clinical Applications

Needs Statement

Physicians, fellows, residents, medical students, and other healthcare professionals need to receive regular updates on practice guidelines, the latest scientific advances, and translational efforts in the field of Obstetrics and Gynecology. The series aims to increase the knowledge and skills of the learners in select topic areas to improve the diagnosis, treatment, and management of obstetric and gynecologic disorders. The series will also address unique ethical challenges in the field.

Educational Objectives

At the conclusion of the session, the participants should be able to:

• Explain the role of endothelial dysfunction in preeclampsia.
• Discuss the molecular mechanisms of endothelial dysfunction.
• Review the current criteria in the diagnosis of preeclampsia and the severe features of hypertensive diseases of pregnancy.
• Summarize the emerging data on the role of vasoactive mediators in the pathogenesis, diagnosis, and treatment of preeclampsia.

Target Audience

Activity Evaluation

Evaluation by questionnaire will address program content, presentation, and possible bias.

Educational Methods

• Lectures

Accreditation/Credit Designation

Baylor College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Baylor College of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Term of Approval

November 1, 2023 through November 30, 2025. Original release date: November 1, 2023.

Disclosure Policy

Baylor College of Medicine (BCM) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians. BCM is committed to sponsoring CE activities that are scientifically based, accurate, current, and objectively presented.

In accordance with the ACCME Standards for Commercial Support, BCM has implemented a mechanism requiring everyone in a position to control the content of an educational activity (i.e., directors, planning committee members, faculty) to disclose any relevant financial relationships with commercial interests (drug/device companies) and manage/resolve any conflicts of interest prior to the activity. Individuals must disclose to participants the existence or non-existence of financial relationships at the time of the activity or within 24 months prior.

In addition, BCM has requested activity faculty/presenters to disclose to participants any unlabeled use or investigational use of pharmaceutical/device products; to use scientific or generic names (not trade names) in referring to products; and, if necessary to use a trade name, to use the names of similar products or those within a class. Faculty/presenters have also been requested to adhere to the ACCME's validation of clinical content statements.

BCM does not view the existence of financial relationships with commercial interests as implying bias or decreasing the value of a presentation. It is up to participants to determine whether the relationships influence the activity faculty with regard to exposition or conclusions. If at any time during this activity you feel that there has been commercial/promotional bias, notify the Activity Director or Activity Coordinator. Please answer the questions about balance and objectivity in the activity evaluation candidly.

All of the relevant financial relationships listed for these individuals have been mitigated.