Liver Allograft Antibody-Mediated Rejection: Reality or Myth?
* You will be redirected to the BCM DCPD credit management site when claiming credit and may be asked to register or log in.
In this presentation, Dr. Jacqueline O'Leary discusses her work in studying donor-specific antibody-mediated tissue rejection in liver transplant recipients. She offers background information on preformed donor-specific antibodies, how they are detected, and what potential impact they can have on the success of a liver transplantation.
This Hepatology and Liver Transplantation Grand Rounds session took place on Tuesday, April 11, 2023 at 7:00 a.m.
Activity Information
How to Claim Credit
You may claim credit after watching this activity.
You will be redirected to the BCM DCPD credit management site when claiming credit and may be asked to register or log in.
Needs Statement
Gastroenterologists, hepatologists, transplant surgeons, internists, advanced practice providers, fellows, residents, and medical students need to receive regular updates on recent advances in the field of Hepatology and Liver Transplantation. The series will highlight new developments in all areas related to liver diseases, changing selection criteria for transplantation, emerging transplantation techniques, and improved immunosuppressive therapies to minimize graft loss and other complications. The series aims to expand the knowledge of learners, promote current clinical and surgical best practices, enhance the quality of hepatology care, improve patient outcomes, and direct future research.
Educational Objectives
At the conclusion of the session, the participants should be able to:
- Discuss the prevalence and risk of preformed donor-specific antibodies.
- Recognize the prevalence of de novo donor-specific antibodies and describe how they affect transplant outcomes.
- Review the criteria for diagnosing both acute and chronic antibody-mediated rejection.
Target Audience
Professional Categories
- Physicians
- Medical Students
- Fellows
- Residents
- Nurses
- Other Health Professionals
Specialties
- Gastroenterology and Hepatology
- Internal Medicine
Interest Groups
- Hospital Medicine
Activity Evaluation
Evaluation by questionnaire will address program content, presentation, and possible bias.
Educational Methods
- Lectures
Accreditation/Credit Designation
Baylor College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Baylor College of Medicine designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Activity Director
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Prasun Kumar Jalal, M.D., MRCP (UK), FAASLD, FASGE
Assistant Professor of Surgery
Baylor College of Medicine
Term of Approval
April 1, 2023 through April 30, 2025. Original release date: April 1, 2023.
Disclosure Policy
Baylor College of Medicine (BCM) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians. BCM is committed to sponsoring CE activities that are scientifically based, accurate, current, and objectively presented.
In accordance with the ACCME Standards for Commercial Support, BCM has implemented a mechanism requiring everyone in a position to control the content of an educational activity (i.e., directors, planning committee members, faculty) to disclose any relevant financial relationships with commercial interests (drug/device companies) and manage/resolve any conflicts of interest prior to the activity. Individuals must disclose to participants the existence or non-existence of financial relationships at the time of the activity or within 24 months prior.
In addition, BCM has requested activity faculty/presenters to disclose to participants any unlabeled use or investigational use of pharmaceutical/device products; to use scientific or generic names (not trade names) in referring to products; and, if necessary to use a trade name, to use the names of similar products or those within a class. Faculty/presenters have also been requested to adhere to the ACCME's validation of clinical content statements.
BCM does not view the existence of financial relationships with commercial interests as implying bias or decreasing the value of a presentation. It is up to participants to determine whether the relationships influence the activity faculty with regard to exposition or conclusions. If at any time during this activity you feel that there has been commercial/promotional bias, notify the Activity Director or Activity Coordinator. Please answer the questions about balance and objectivity in the activity evaluation candidly.
All of the relevant financial relationships listed for these individuals have been mitigated.
Disclosures
The following individual(s) has/have reported financial or other relationship(s) with commercial entities whose products/services may relate to the educational content of this activity:
Presenter
-
Jacqueline O-Leary, M.D., M.P.H.
Associate Professor of Internal Medicine
University of Texas Southwestern Medical Center
Disclosure:
- Research Support: Grifols; Salix
- Consultancy: AbbVie; Genfit; Gilead; Grifols; Mallinckrodt
- Ownership Interests (stock, stock options, excluding diversified mutual funds): CVS (stockholder)
Activity Director
-
Prasun Kumar Jalal, M.D., MRCP (UK), FAASLD, FASGE
Assistant Professor of Surgery
Baylor College of Medicine
Disclosure:
- Advisory Committee Membership: Abbvie; Alexion; Albireo; Gilead
- Honorarium Recipient: Abbvie
Planning Committee Members
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Prasun Kumar Jalal, M.D., MRCP (UK), FAASLD, FASGE
Assistant Professor of Surgery
Baylor College of Medicine
Disclosure:
Nothing to disclose.
-
Ashlie Kaim, MPAS, PA-C
Assistant Professor
Baylor College of Medicine
Disclosure:
Nothing to disclose.
-
Saira Aijaz Khaderi, M.D., M.P.H.
Assistant Professor of Surgery
Baylor College of Medicine
Disclosure:
Nothing to disclose.
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Gagan K Sood, M.D.
Professor of Medicine, Section of Gastroenterology and Hepatology; Professor of Surgery, Division of Abdominal Transplantation
Baylor College of Medicine
Disclosure:
Nothing to disclose.
Health Topics
Presenter: