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Recruiting
Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors (External Link)
The growing prevalence of obesity in older adults including many older Veterans, has become a major concern in the US already strained health care system in general and in the …
Baylor Role: Collaborator
Completed
The i Heart Rhythm Project: Healthy Sleep and Behavioral Rhythms for Obesity Prevention (External Link)
The current study employs a 2 group randomized control design (treatment and no-treatment control) with randomization occurring after baseline (time 0) and 3 additional evaluation periods (end of intervention (time …
Baylor Role: Lead Sponsor
Recruiting
Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity (External Link)
This study aims to evaluate the effects of oral glycine supplementation on plasma glycine concentration, intracellular glutathione (GSH) concentration, plasma acylglycine concentration, urine acylglycine concentration, and insulin resistance in subjects …
Baylor Role: Collaborator
Recruiting
Genetic Disorders of Obesity Program Database (External Link)
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children …
Baylor Role: Lead Sponsor
Recruiting
Causal Mechanisms in Adolescent Arterial Stiffness (External Link)
Aortic stiffness measured in adolescence or adulthood determines current hypertension, predicts future incidence of hypertension, and future atherosclerotic cardiovascular disease (ASCVD) events. International hypertension guidelines list severe aortic stiffness as …
Baylor Role: Lead Sponsor
Recruiting
Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program? (External Link)
AIM 1: We will categorize children ages 7-12 yrs. of age with FGIDs (n=250) as to whether they have/do not have one or more of the following abnormal physiologic changes: …
Baylor Role: Lead Sponsor
Completed
Obesity-Related Glycine Deficiency: Investigating a Long-standing Metabolic Paradox Using Bedside and Bench Approaches (External Link)
Metabolic tracers: 1,2-[13C2]-Glycine, 1,2-[13C2]-Glycine, 2,3,3,-[2H3]-Serine and [2H5]-Phenylalanine will be infused for quantification of various pathways associated with glycine metabolism.
Baylor Role: Collaborator
Completed
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers (External Link)
Screen time is a major risk factor for childhood obesity and inadequate physical activity, both of which are determinants of type 2 diabetes (T2D), cardiovascular disease, and multiple cancers. Latinos …
Baylor Role: Collaborator
Recruiting
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism (External Link)
After age of 40, testosterone (T) production in men gradually decreases at a rate of 1.6% per year for total and to 2-3% per year for bioavailable T. This reduction …
Baylor Role: Lead Sponsor
Completed
Online Videos and New Feeding Content to Enhance a Current EFNEP Program (External Link)
During Phase I of the project (first two years), the leadership team composed of both research and extension investigators will work with the media production team to edit the SEEDS …
Baylor Role: Lead Sponsor