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9 Results
Not Yet Recruiting
A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults
The study rationale is that prior to conducting a multisite randomized trial, it is necessary to identify relevant outcomes, understand barriers to greater use of local anesthesia, test study procedures, …
Baylor Role: Collaborator
Recruiting
Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial
Gastroschisis is a congenital abdominal wall defect by which the intestinal structures eviscerate from the abdomen, with a current prevalence of 4.9 per 10,000 pregnancies in the United States. Not …
Baylor Role: Lead Sponsor
Recruiting
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH
Enrollment Women carrying a fetus with severe CDH and a normal karyotype will undergo routine clinical evaluation. The fetus will be 28+0/7 to 31+6/7 weeks of gestational age and have …
Baylor Role: Collaborator
Active, Not Recruiting
Oral Care in Infants With Gastroschisis
Breast milk is recommended for most infants by the American Academy of Pediatrics as there are multiple benefits. However, some infants, such as extremely premature infants, are unable to receive …
Baylor Role: Lead Sponsor
Completed
'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial
This is a multi-center, non-blinded randomized controlled trial in fetuses with isolated moderate CDH, i.e. moderate lung hypoplasia (as determined by prenatal assessment of lung development). It essentially compares fetal …
Baylor Role: Collaborator
Terminated
Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine Care
Gastroschisis is a congenital malformation in which abdominal organs protrude through an abdominal wall defect, leading to considerable morbidity and mortality during infancy. In contrast to the second class of …
Baylor Role: Lead Sponsor
Completed
Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic Hernia
Enrollment Women carrying fetuses with severe or extremely severe CDH and a normal karyotype will undergo routine clinical evaluation. The fetuses will be 27+0/7 to 29+6/7 weeks of gestational age …
Baylor Role: Collaborator
Completed
Fetal Surgery for Moderate Left Sided Congenital Diaphragmatic Hernia.
Isolated Congenital Diaphragmatic Hernia (CDH) can be diagnosed in the prenatal period, and remains associated with a 30 % chance of perinatal death and morbidity mainly because of pulmonary hypoplasia …
Baylor Role: Collaborator
Completed
Watchful Waiting of Incisional Hernias
This study is being conducted to gain a better understanding of the quality of life for patients with a diagnosis of primary and recurrent incisional hernias and 1) who decline …
Baylor Role: Lead Sponsor