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Terminated
Primary Versus Delayed Surgical Therapy for Pediatric Spontaneous Pneumothorax
1. All children presenting to Texas Children's Hospital with a primary spontaneous pneumothorax will be potentially eligible for the study. 2. After the diagnosis has been made and initial medical …
Baylor Role: Lead Sponsor
Terminated
Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM
TREATMENT PLAN PREOPERATIVE HYDRATION According to our observations, preoperative hydration reduces the risk of nephrotoxicity from intrathoracic infusion of hyperthermic cisplatin. Therefore, all patients will be admitted the night before …
Baylor Role: Lead Sponsor
Terminated
Safety and Efficacy of Saracatinib In Subjects With Lymphangioleiomyomatosis
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in tuberous sclerosis complex 1 (TSC1) or TSC2 tumor suppressor genes. TSC is characterized by tumors in a …
Baylor Role: Lead Sponsor
Terminated
Adjunctive Transcranial Direct Current Stimulation
Chronic or persistent pain is pain that continues when it should not be present; it is ongoing or recurrent pain, lasting beyond the usual course of acute illness or injury, …
Baylor Role: Lead Sponsor
Terminated
Effect of Dapagliflozin on Inflammation and Endothelial Function
The insulin-resistant state of type 2 diabetes mellitus (T2DM) is largely mediated by inflammatory pathways affecting skeletal muscle which is the primary site of whole body insulin resistance. Nuclear factor …
Baylor Role: Lead Sponsor
Terminated
Treatment of Adult Patients With Hemoglobin SC Disease (SCYTHE)
Patients will be recruited from the patient population followed at the Texas Children's Cancer and Hematology Centers (TCC/HC)/Baylor College of Medicine (BCM) and the University of Texas Houston Hematology Center. …
Baylor Role: Lead Sponsor
Terminated
Transcorporal Versus Standard Artificial Urinary Sphincter Placement
Procedure/ Methods: Patients will be identified in the urology clinic upon their standard of care visit for AUS placement. The procedures that determine whether a patient is a surgical candidate …
Baylor Role: Collaborator
Terminated
Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft
Urethral strictures affect 1% of men and are rare in women. Most urethral strictures in the United States develop in the bulbar section of the urethra which is the section …
Baylor Role: Collaborator
Terminated
The Utility of Time Segmental Withdrawal During Screening Colonoscopy for Increasing Adenoma Detection Rate.
Screening colonoscopy is an essential diagnostic tool in the early detection of precancerous colonic lesions, preventing the progression of these lesions to cancer. Population-based and case control studies found a …
Baylor Role: Lead Sponsor
Terminated
Human Optokinetic Contrast Device (HOCD) to Measure Visual Function and Identify Patients With and Without Glaucoma
The protocol is divided into two studies that will have two separate consent forms (Study 1 and Study 2). Study 1 involves the optimization of the device parameters. Study 1 …