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Terminated
Postoperative Chemoradiation or Chemotherapy After Preoperative Chemotherapy for Gastric Cancers
Gastric adenocarcinoma, also known as stomach cancer, is a global health problem. While surgical resection remains the only curative option for patients who develop this disease, because of its aggressive …
Terminated
Coaching and Education for Diabetes Distress
Diabetes distress (DD) is a negative emotional reaction to a diagnosis of diabetes and concerns about the burden of managing diabetes, the risk of complications, and inadequate support system. DD …
Baylor Role: Lead Sponsor
Terminated
Primary Versus Delayed Surgical Therapy for Pediatric Spontaneous Pneumothorax
1. All children presenting to Texas Children's Hospital with a primary spontaneous pneumothorax will be potentially eligible for the study. 2. After the diagnosis has been made and initial medical …
Baylor Role: Lead Sponsor
Terminated
Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM
TREATMENT PLAN PREOPERATIVE HYDRATION According to our observations, preoperative hydration reduces the risk of nephrotoxicity from intrathoracic infusion of hyperthermic cisplatin. Therefore, all patients will be admitted the night before …
Baylor Role: Lead Sponsor
Terminated
Non-Invasive Direct Current Stimulation for Cognition in Schizophrenia
Cognitive functions and EEG correlates will be thoroughly assessed in schizophrenia patients undergoing a tDCS treatment and compared with patients receiving a placebo stimulation. The treatment will involve 20 minutes …
Baylor Role: Lead Sponsor
Terminated
Safety and Efficacy of Saracatinib In Subjects With Lymphangioleiomyomatosis
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in tuberous sclerosis complex 1 (TSC1) or TSC2 tumor suppressor genes. TSC is characterized by tumors in a …
Baylor Role: Lead Sponsor
Terminated
Hummus for Health: Dietary Quality and Health Outcomes in Toddlers
Population: The investigators will recruit 104 children ages 12-24 months from daycare centers in the Houston and surrounding areas. Study design: The study will be conducted at daycare centers and …
Baylor Role: Lead Sponsor
Terminated
Adjunctive Transcranial Direct Current Stimulation
Chronic or persistent pain is pain that continues when it should not be present; it is ongoing or recurrent pain, lasting beyond the usual course of acute illness or injury, …
Baylor Role: Lead Sponsor
Terminated
Effect of Dapagliflozin on Inflammation and Endothelial Function
The insulin-resistant state of type 2 diabetes mellitus (T2DM) is largely mediated by inflammatory pathways affecting skeletal muscle which is the primary site of whole body insulin resistance. Nuclear factor …
Baylor Role: Lead Sponsor
Terminated
Treatment of Adult Patients With Hemoglobin SC Disease (SCYTHE)
Patients will be recruited from the patient population followed at the Texas Children's Cancer and Hematology Centers (TCC/HC)/Baylor College of Medicine (BCM) and the University of Texas Houston Hematology Center. …
Baylor Role: Lead Sponsor