Search Clinical Trials
Recruiting
Hepatic Histopathology in Urea Cycle Disorders (External Link)
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism. With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this …
Baylor Role:
Lead Sponsor
Recruiting
Liver Disease in Urea Cycle Disorders (External Link)
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism. With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this …
Baylor Role:
Lead Sponsor
Recruiting
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes (External Link)
Type 2 diabetes is an increasingly common disease that affects more than 10 percent of adults in the United States. Multiple medications are available to treat this condition. However, many …
Baylor Role:
Collaborator
Recruiting
Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors (External Link)
The growing prevalence of obesity in older adults including many older Veterans, has become a major concern in the US already strained health care system in general and in the …
Baylor Role:
Collaborator
Recruiting
L-Citrulline Dose Finding Safety Study in MELAS (External Link)
The human body is made of many cells and each cell contains many mitochondria. Mitochondria are called the powerhouses of the cell, because they produce the energy needed for a …
Baylor Role:
Lead Sponsor
Recruiting
Fit 24 Technology Intervention YOUTH (External Link)
Hispanic adolescents are disproportionately burdened by obesity and type 2 diabetes compared to non-Hispanic white youth. Disparities in T2D emerge early in life and are driven in part by unhealthy …
Baylor Role:
Lead Sponsor
Recruiting
Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity (External Link)
This study aims to evaluate the effects of oral glycine supplementation on plasma glycine concentration, intracellular glutathione (GSH) concentration, plasma acylglycine concentration, urine acylglycine concentration, and insulin resistance in subjects …
Baylor Role:
Collaborator
Recruiting
Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress (External Link)
This research study looks to enroll as many people with LFS or TP53 gene variants as possible in order to: - Better estimate cancer risks in individuals with TP53 variants …
Baylor Role:
Collaborator
Recruiting
Genetic Disorders of Obesity Program Database (External Link)
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children …
Baylor Role:
Lead Sponsor
Recruiting
Causal Mechanisms in Adolescent Arterial Stiffness (External Link)
Aortic stiffness measured in adolescence or adulthood determines current hypertension, predicts future incidence of hypertension, and future atherosclerotic cardiovascular disease (ASCVD) events. International hypertension guidelines list severe aortic stiffness as …
Baylor Role:
Lead Sponsor